Parkinsonism |
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Parkinsonism is a group of neurological disorders characterized by hypokinesia, tremor and muscular rigidity. Its most common form (Parkinson’s disease) is paralysis agitans, usually occurring in late life. There is degeneration within the nuclear masses of the extrapyramidal system and a characteristic reduction in dopamine levels. It is a slowly progressive disease characterized by mask like facies, a tremor of resting muscles, a slowing of voluntary movements, a festinating gait and peculiar posture. There may be excessive sweating and heat sensations. Although the disease cannot be cured, there are various agents which can relieve its symptoms, the most common of which are levodopa and anticholinergic drugs. Products: Antiparkinson agents
Adamantan
Amantadine is a synthetic (man-made) anti-viral drug that can inhibit the replication of viruses in cells. To prevent a viral infection, the drug should be present before exposure to the virus. Clearly, this is not practical for most viral infections. It was initially used to prevent influenza A during flu season, and, if given within 24 to 48 hours of the onset of flu symptoms, to decrease the severity of the flu. Later amantadine was found to cause improvement in the symptoms of Parkinson's disease. Amantadine's mechanism of action in Parkinson's disease is not fully understood. Its effects may be related to its ability to augment (amplify) the effects of dopamine, a neurotransmitter in the brain, that is reduced in Parkinson's disease. Amantadine is less effective than levodopa in Parkinson's disease but can offer additional benefit when taken with levodopa. Amantadine was approved by the FDA in 1966.
Bromocriptine
Bromocriptine (also known as Parlodel) is a potent prolactin inhibitor and also acts as dopaminomimetic, so it is also used to treat people who have Parkinson’s disease.
Deprenyl
Deprenyl works by helping to conserve the amount of dopamine available by preventing the dopamine from being destroyed. While controversial, there is some evidence that this drug may slow the progression of Parkinson's disease, particularly early in the course of the disease.
Jumex
Jumex (Selegiline), also known as Deprenyl, Eldepryl works by helping to conserve the amount of dopamine available by preventing the dopamine from being destroyed. While controversial, there is some evidence that this drug may slow the progression of Parkinson's disease, particularly early in the course of the disease.
Madopar
The name of your medicine is MADOPAR. It contains two active ingredients called levodopa and benserazide. MADOPAR belongs to a group of medicines called antiparkinsonian agents.
Mirapexin
Mirapex eases the symptoms of Parkinson's disease - a progressive disorder marked by muscle rigidity, weakness, shaking, tremor, and eventually difficulty with walking and talking. Parkinson's disease results from a shortage of the chemical messenger dopamine in certain areas of the brain. Mirapex is believed to work by boosting the action of whatever dopamine is available. The drug can be used with other Parkinson's medications such as Eldepryl, Sinemet, and Larodopa.
Selegilin
Selegiline (known as Jumex in Europe)protects against aging of the brain, enhances mental function. A powerful remedy against Parkinson's disease, Selegiline is effective also as an antidepressant and as a protector against Alzheimer's disease. Professor Knoll, who developed Selegiline is convinced of its anti-aging effect and recommends for this a dose 5 mg per week (in two doses of 2.5 mg each).
Packing: Box of 30 tablets, 5 mg
Sinemet
Sinemet CR is a controlled-release tablet that may be given to help relieve the muscle stiffness, tremor, and weakness caused by Parkinson's disease. It may also be given to relieve Parkinson-like symptoms caused by encephalitis (brain fever), carbon monoxide poisoning, or manganese poisoning.
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