Rhodiola root scientific update |
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J Strength Cond Res. 2005 May;19(2):358-63.
Colson SN, Wyatt FB, Johnston DL, Autrey LD, Fitzgerald YL, Earnest CP.
Department of Health Sciences, McLennan Community College, Waco, Texas 76708, USA.
Cordyceps sinensis- and Rhodiola rosea-based supplementation in male cyclists and its effect on muscle tissue oxygen saturation.
Cordyceps sinensis (Cs) and Rhodiola rosea (Rr) are herbs used in traditional Chinese medicine to treat a multitude of ailments as well as to enhance performance. The purpose of this research was to examine the effects of a formula containing Cs and Rr (Cs-Rr) on circulatory dynamics, specifically muscle tissue oxygen saturation (Sto(2)), in male subjects during maximal exercise. This study followed a double blind, randomized, placebo-treatment, pre-post test design. Capsules were administered to 8 subjects who were randomly assigned to 1 of 2 groups. The treatment group received Cs-Rr, and the control group received a placebo. All subjects performed 2 exercise stress tests to volitional fatigue on a cycle load ergometer. There were no significant (p
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2005 May;25(5):445-8.
Li J, Fan WH, Ao H.
Department of Cardiac Diseases, Huashan Hospital, Fudan University, Shanghai.
Effect of rhodiola on expressions of Flt-1, KDR and Tie-2 in rats with ischemic myocardium.
OBJECTIVE: To investigate the effect of rhodiola on expression of vascular endothelial growth factors receptors (VEGFR) in myocardium of rats after myocardial infarction. METHODS: On the basis of successful establishment of myocardial infarction rat model, the experimental animals were divided into the model group, the rhodiola group, the positive control group and the sham-operated group, they were sacrificed after 6 weeks feeding. Their hearts were resected and embedded in paraffin to make sections with standard immunohistochemistry stain. Then the stained slices were analyzed in the IMS cell imagine analysis system using immunohistochemical quantitative analysis software. The field of vision of left ventricular myocardial tissue in three sites selected from the marginal area of infarction in each slice were determined, the mean value was then converted to positive area. Meanwhile, the mean optical density (OD) was calculated and the various expressions of VEGFR, i.e. Flt-1, KDR and angiopoietin receptor (Tie-2) were measured. RESULTS: The expressions of Flt-1 and Tie-2 in myocardial tissue were significantly increased in the rhodiola treated group after treatment, showing significant difference as compared with those in the positive control group and the model group (P < 0.05). The expression of KDR in myocardium after rhodiola intervention was higher than that in the sham-operated and nonintervened group (P < 0.05), but insignificantly different to that in the positive control group and model group. CONCLUSION: Rhodiola could improve angiogenesis to ameliorate myocardial ischemia by regulating the expression of Flt-1 and Tie-2 in ischemic myocardium.
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Drug category:Antidepressants
 Rhodiola root scientific update
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